Langara College courses and programs were first offered in 1965 at King Edward Centre as part of Vancouver City College. The current site at West 49th Avenue has housed the programs since 1970. Langara College was established as an independent public college under the Provincial College and Institute Act on April 1, 1994.

In 2019 Langara celebrated it's 49th anniversary on West 49th avenue, and it's 25th anniversary as an independent public institution with Beyond 49, an innovative alumni engagement, fundraising, and anniversary celebration campaign. The College's proud history is shared on the interactive campaign website.